Pain Relief - Diclofenac
Diclofenac
Diclofenac is a nonsteroidal anti-inflammatory drug (NSAID) available in topical formulations such as gels and transdermal patches. It is used to relieve localized pain, stiffness, and inflammation associated with osteoarthritis, joint injuries, back pain, and soft tissue conditions. Unlike oral NSAIDs, topical diclofenac delivers medication directly to the affected area with significantly reduced systemic exposure—minimizing gastrointestinal and cardiovascular side effects. It is commonly used for knee, elbow, wrist, shoulder, and lower back pain.
How does it work
Topical Diclofenac provides anti-inflammatory and analgesic effects at the site of pain:
- COX Enzyme Inhibition
• Diclofenac blocks the cyclooxygenase (COX-1 and COX-2) enzymes, reducing production of prostaglandins—chemical messengers that cause pain and inflammation in injured or arthritic tissues. - Localized Absorption = Targeted Relief
• The medication penetrates skin and soft tissue, concentrating at the site of pain while minimizing systemic absorption, which reduces risks of GI upset, bleeding, or cardiovascular effects. - Long-Acting Patch Option
• The transdermal patch delivers sustained diclofenac over 12–24 hours for ongoing relief without the need for frequent reapplication.
Benefits
✓ Fast-acting pain relief directly at the source
✓ Reduces swelling, stiffness, and inflammation
✓ Lower risk of GI or cardiovascular side effects vs. oral NSAIDs
✓ Available in gel or patch form for patient preference
✓ Ideal for joint, tendon, and soft tissue pain
✓ Well tolerated for long-term use in localized areas
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Frequently Asked Questions
What can I expect when using Diclofenac?
- Pain relief may begin within 30–60 minutes of application
- Best results with consistent use 2–4 times daily (gel) or once every 12–24 hours (patch)
- Reduced swelling, stiffness, and improved function over several days
- For chronic use (e.g., arthritis), full benefit often seen within 7–10 days
- Do not apply more than prescribed or cover with occlusive dressings unless instructed
What are the possible side effects of Diclofenac?
Common (Usually Mild & Localized):
- Application site itching, redness, or rash
- Dryness or peeling
- Mild burning or stinging sensation
Less Common:
- Photosensitivity (sun sensitivity)
- Allergic skin reaction
- Rare systemic NSAID effects if applied to large areas or broken skin
Precautions:
- Avoid applications to open wounds, eyes, or mucous membranes
- Do not use oral NSAIDs concurrently without provider approval
- Wash hands after application unless hands are the treatment site
- Limit sun exposure on treated areas
